BDBM50172140 (S)-2-Amino-2-cyclohexyl-1-((3S,4S)-3,4-difluoro-pyrrolidin-1-yl)-ethanone::CHEMBL372115
SMILES: N[C@@H](C1CCCCC1)C(=O)N1C[C@H](F)[C@@H](F)C1
InChI Key: InChIKey=KSMDMFVYXQVQCE-DCAQKATOSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50172140 ((S)-2-Amino-2-cyclohexyl-1-((3S,4S)-3,4-difluoro-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity | Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0 | |||||||||||
More data for this Ligand-Target Pair |