BDBM50172268 4-(3-(S)-1-Pyrrolidin-2-ylmethyl-indole-1-sulfonyl)-phenylamine::CHEMBL427184

SMILES: Nc1ccc(cc1)S(=O)(=O)n1cc(C[C@@H]2CCCN2)c2ccccc12

InChI Key: InChIKey=QDSCCNYUEDYRQW-INIZCTEOSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172268 (4-(3-(S)-1-Pyrrolidin-2-ylmethyl-indole-1-sulfonyl...) Show SMILES Nc1ccc(cc1)S(=O)(=O)n1cc(C[C@@H]2CCCN2)c2ccccc12 Show InChI InChI=1S/C19H21N3O2S/c20-15-7-9-17(10-8-15)25(23,24)22-13-14(12-16-4-3-11-21-16)18-5-1-2-6-19(18)22/h1-2,5-10,13,16,21H,3-4,11-12,20H2/t16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172268 (4-(3-(S)-1-Pyrrolidin-2-ylmethyl-indole-1-sulfonyl...) Show SMILES Nc1ccc(cc1)S(=O)(=O)n1cc(C[C@@H]2CCCN2)c2ccccc12 Show InChI InChI=1S/C19H21N3O2S/c20-15-7-9-17(10-8-15)25(23,24)22-13-14(12-16-4-3-11-21-16)18-5-1-2-6-19(18)22/h1-2,5-10,13,16,21H,3-4,11-12,20H2/t16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptor				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair