null

SMILES: Fc1ccccc1S(=O)(=O)n1cc(C2=CCCNC2)c2ccccc12

InChI Key: InChIKey=JRYJFXSUNKFRJM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172281 (1-(2-Fluoro-benzenesulfonyl)-3-(1,2,5,6-tetrahydro...) Show SMILES Fc1ccccc1S(=O)(=O)n1cc(C2=CCCNC2)c2ccccc12 |t:14| Show InChI InChI=1S/C19H17FN2O2S/c20-17-8-2-4-10-19(17)25(23,24)22-13-16(14-6-5-11-21-12-14)15-7-1-3-9-18(15)22/h1-4,6-10,13,21H,5,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172281 (1-(2-Fluoro-benzenesulfonyl)-3-(1,2,5,6-tetrahydro...) Show SMILES Fc1ccccc1S(=O)(=O)n1cc(C2=CCCNC2)c2ccccc12 |t:14| Show InChI InChI=1S/C19H17FN2O2S/c20-17-8-2-4-10-19(17)25(23,24)22-13-16(14-6-5-11-21-12-14)15-7-1-3-9-18(15)22/h1-4,6-10,13,21H,5,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptors				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair