BDBM50172302 1-(3,4-Difluoro-benzenesulfonyl)-3-piperidin-3-yl-1H-indole::CHEMBL363843

SMILES: Fc1ccc(cc1F)S(=O)(=O)n1cc(C2CCCNC2)c2ccccc12

InChI Key: InChIKey=WYIXSNCSCVYJDE-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172302 (1-(3,4-Difluoro-benzenesulfonyl)-3-piperidin-3-yl-...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)n1cc(C2CCCNC2)c2ccccc12 Show InChI InChI=1S/C19H18F2N2O2S/c20-17-8-7-14(10-18(17)21)26(24,25)23-12-16(13-4-3-9-22-11-13)15-5-1-2-6-19(15)23/h1-2,5-8,10,12-13,22H,3-4,9,11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50172302 (1-(3,4-Difluoro-benzenesulfonyl)-3-piperidin-3-yl-...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)n1cc(C2CCCNC2)c2ccccc12 Show InChI InChI=1S/C19H18F2N2O2S/c20-17-8-7-14(10-18(17)21)26(24,25)23-12-16(13-4-3-9-22-11-13)15-5-1-2-6-19(15)23/h1-2,5-8,10,12-13,22H,3-4,9,11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	66	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptors				Bioorg Med Chem Lett 15: 4780-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.028 BindingDB Entry DOI: 10.7270/Q2RN37DD
					More data for this Ligand-Target Pair