BDBM50172419 (E)-N-{2-[(2-Dimethylamino-ethyl)-methyl-amino]-quinolin-6-yl}-3-p-tolyl-acrylamide::CHEMBL194477

SMILES: CN(C)CCN(C)c1ccc2cc(NC(=O)\C=C\c3ccc(C)cc3)ccc2n1

InChI Key: InChIKey=GEGLJDPEPGLWCZ-NTEUORMPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50172419 ((E)-N-{2-[(2-Dimethylamino-ethyl)-methyl-amino]-qu...) Show SMILES CN(C)CCN(C)c1ccc2cc(NC(=O)\C=C\c3ccc(C)cc3)ccc2n1 Show InChI InChI=1S/C24H28N4O/c1-18-5-7-19(8-6-18)9-14-24(29)25-21-11-12-22-20(17-21)10-13-23(26-22)28(4)16-15-27(2)3/h5-14,17H,15-16H2,1-4H3,(H,25,29)/b14-9+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	804	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50172419 ((E)-N-{2-[(2-Dimethylamino-ethyl)-methyl-amino]-qu...) Show SMILES CN(C)CCN(C)c1ccc2cc(NC(=O)\C=C\c3ccc(C)cc3)ccc2n1 Show InChI InChI=1S/C24H28N4O/c1-18-5-7-19(8-6-18)9-14-24(29)25-21-11-12-22-20(17-21)10-13-23(26-22)28(4)16-15-27(2)3/h5-14,17H,15-16H2,1-4H3,(H,25,29)/b14-9+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair