BDBM50172451 (E)-3-(3-Chloro-phenyl)-N-[4-methyl-2-(4-methyl-piperazin-1-yl)-quinolin-6-yl]-acrylamide::CHEMBL198823

SMILES: CN1CCN(CC1)c1cc(C)c2cc(NC(=O)\C=C\c3cccc(Cl)c3)ccc2n1

InChI Key: InChIKey=GQWRCNJAHPBIRB-RMKNXTFCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50172451 ((E)-3-(3-Chloro-phenyl)-N-[4-methyl-2-(4-methyl-pi...) Show SMILES CN1CCN(CC1)c1cc(C)c2cc(NC(=O)\C=C\c3cccc(Cl)c3)ccc2n1 Show InChI InChI=1S/C24H25ClN4O/c1-17-14-23(29-12-10-28(2)11-13-29)27-22-8-7-20(16-21(17)22)26-24(30)9-6-18-4-3-5-19(25)15-18/h3-9,14-16H,10-13H2,1-2H3,(H,26,30)/b9-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair