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SMILES: CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)c3cc(nc4ccccc34)-c3cccs3)ccc2n1

InChI Key: InChIKey=MPLFGSSKQRHUCS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172453   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50172453
PNG
(2-Thiophen-2-yl-quinoline-4-carboxylic acid [2-(4-...)
Show SMILES CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)c3cc(nc4ccccc34)-c3cccs3)ccc2n1
Show InChI InChI=1S/C30H29N5OS/c1-3-34-12-14-35(15-13-34)29-17-20(2)23-18-21(10-11-26(23)33-29)31-30(36)24-19-27(28-9-6-16-37-28)32-25-8-5-4-7-22(24)25/h4-11,16-19H,3,12-15H2,1-2H3,(H,31,36)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.48E+4n/an/an/an/an/an/a



7TM Pharma A/S

Curated by ChEMBL


Assay Description
Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells

J Med Chem 48: 5684-97 (2005)


Article DOI: 10.1021/jm050103y
BindingDB Entry DOI: 10.7270/Q2H41QZ8
More data for this
Ligand-Target Pair