BDBM50172912 (S)-2-(2-Piperidin-1-yl-ethyl)-1,5,10,10a-tetrahydro-2H-imidazo[1,5-b]isoquinolin-3-one::CHEMBL439859

SMILES: O=C1N(CCN2CCCCC2)C[C@@H]2Cc3ccccc3CN12

InChI Key: InChIKey=NYRUMQLDGMIGKK-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50172912 ((S)-2-(2-Piperidin-1-yl-ethyl)-1,5,10,10a-tetrahyd...) Show SMILES O=C1N(CCN2CCCCC2)C[C@@H]2Cc3ccccc3CN12 Show InChI InChI=1S/C18H25N3O/c22-18-20(11-10-19-8-4-1-5-9-19)14-17-12-15-6-2-3-7-16(15)13-21(17)18/h2-3,6-7,17H,1,4-5,8-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lille II Curated by ChEMBL					Assay Description Inhibitory concentration against opioid receptor sigma 1 of guinea pig cerebral cortex using [3H]-(+)-pentazocine upon incubation for 150 minutes at ...				Bioorg Med Chem Lett 15: 4833-7 (2005) Article DOI: 10.1016/j.bmcl.2005.07.040 BindingDB Entry DOI: 10.7270/Q2PN9553
					More data for this Ligand-Target Pair