BDBM50173025 4-[4-(4-Carbamoyl-phenyl)-phthalazin-1-ylamino]-benzoic acid methyl ester::CHEMBL196610::methyl 4-(4-(4-carbamoylphenyl)phthalazin-1-ylamino)benzoate

SMILES: COC(=O)c1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)cc1

InChI Key: InChIKey=BPTRMWHKPOMVMB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173025 (4-[4-(4-Carbamoyl-phenyl)-phthalazin-1-ylamino]-be...) Show SMILES COC(=O)c1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)cc1 Show InChI InChI=1S/C23H18N4O3/c1-30-23(29)16-10-12-17(13-11-16)25-22-19-5-3-2-4-18(19)20(26-27-22)14-6-8-15(9-7-14)21(24)28/h2-13H,1H3,(H2,24,28)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF method				Bioorg Med Chem 17: 731-40 (2009) Article DOI: 10.1016/j.bmc.2008.11.049 BindingDB Entry DOI: 10.7270/Q2W95929
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173025 (4-[4-(4-Carbamoyl-phenyl)-phthalazin-1-ylamino]-be...) Show SMILES COC(=O)c1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)cc1 Show InChI InChI=1S/C23H18N4O3/c1-30-23(29)16-10-12-17(13-11-16)25-22-19-5-3-2-4-18(19)20(26-27-22)14-6-8-15(9-7-14)21(24)28/h2-13H,1H3,(H2,24,28)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide				Bioorg Med Chem Lett 15: 4696-8 (2005) Article DOI: 10.1016/j.bmcl.2005.07.064 BindingDB Entry DOI: 10.7270/Q25Q4VNS
					More data for this Ligand-Target Pair