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SMILES: NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(cc2)S(N)(=O)=O)c2ccccc12

InChI Key: InChIKey=CPOUJZWZCROKKO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173030   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50173030
PNG
(4-[4-(4-Sulfamoyl-phenylamino)-phthalazin-1-yl]-be...)
Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(cc2)S(N)(=O)=O)c2ccccc12
Show InChI InChI=1S/C21H17N5O3S/c22-20(27)14-7-5-13(6-8-14)19-17-3-1-2-4-18(17)21(26-25-19)24-15-9-11-16(12-10-15)30(23,28)29/h1-12H,(H2,22,27)(H,24,26)(H2,23,28,29)
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



ImClone Systems

Curated by ChEMBL


Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide

Bioorg Med Chem Lett 15: 4696-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS
More data for this
Ligand-Target Pair