BDBM50173168 4-[(S)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxymethyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl]-pyrimidin-2-ylamine::CHEMBL372082

SMILES: COc1ccc(COC[C@@H]2CCc3nc(c(-c4ccnc(N)n4)n23)-c2ccc(F)cc2)cc1

InChI Key: InChIKey=BKLYUVKUMMLBIJ-IBGZPJMESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173168   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50173168 (4-[(S)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...) Show SMILES COc1ccc(COC[C@@H]2CCc3nc(c(-c4ccnc(N)n4)n23)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H24FN5O2/c1-32-20-9-2-16(3-10-20)14-33-15-19-8-11-22-30-23(17-4-6-18(26)7-5-17)24(31(19)22)21-12-13-28-25(27)29-21/h2-7,9-10,12-13,19H,8,11,14-15H2,1H3,(H2,27,28,29)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against p38 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50173168 (4-[(S)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...) Show SMILES COc1ccc(COC[C@@H]2CCc3nc(c(-c4ccnc(N)n4)n23)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H24FN5O2/c1-32-20-9-2-16(3-10-20)14-33-15-19-8-11-22-30-23(17-4-6-18(26)7-5-17)24(31(19)22)21-12-13-28-25(27)29-21/h2-7,9-10,12-13,19H,8,11,14-15H2,1H3,(H2,27,28,29)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	61.2	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair