BDBM50173200 8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyrazine-6-carboxylic acid benzyl-methyl-amide::CHEMBL197249

SMILES: CN(Cc1ccccc1)C(=O)c1cn2nc(nc2c(N)n1)-c1ccco1

InChI Key: InChIKey=UGUDIPNIJOGKMR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50173200 (8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyrazin...) Show SMILES CN(Cc1ccccc1)C(=O)c1cn2nc(nc2c(N)n1)-c1ccco1 Show InChI InChI=1S/C18H16N6O2/c1-23(10-12-6-3-2-4-7-12)18(25)13-11-24-17(15(19)20-13)21-16(22-24)14-8-5-9-26-14/h2-9,11H,10H2,1H3,(H2,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Binding affinity towards adenosine A2a receptor of rat brain homogenates using [3H]-ZM-241,385 compared to SCH-58261 (Ki=37 nM)				Bioorg Med Chem Lett 15: 4809-13 (2005) Article DOI: 10.1016/j.bmcl.2005.07.052 BindingDB Entry DOI: 10.7270/Q24Q7TJV
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50173200 (8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyrazin...) Show SMILES CN(Cc1ccccc1)C(=O)c1cn2nc(nc2c(N)n1)-c1ccco1 Show InChI InChI=1S/C18H16N6O2/c1-23(10-12-6-3-2-4-7-12)18(25)13-11-24-17(15(19)20-13)21-16(22-24)14-8-5-9-26-14/h2-9,11H,10H2,1H3,(H2,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Binding affinity towards adenosine A1 receptor of rat cerebral cortex using [3H]-DPCPX compared to SCH-58261 (Ki=390 nM)				Bioorg Med Chem Lett 15: 4809-13 (2005) Article DOI: 10.1016/j.bmcl.2005.07.052 BindingDB Entry DOI: 10.7270/Q24Q7TJV
					More data for this Ligand-Target Pair