BDBM50173277 1'-cyclooctylmethyl-1-(4-methoxybenzyl)spiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-2-one::CHEMBL383371

SMILES: COc1ccc(CN2C(=O)C3(CCN(CC4CCCCCCC4)CC3)c3ccccc23)cc1

InChI Key: InChIKey=NRSRBKMPGXYFDE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50173277 (1'-cyclooctylmethyl-1-(4-methoxybenzyl)spiro[2,3-d...) Show SMILES COc1ccc(CN2C(=O)C3(CCN(CC4CCCCCCC4)CC3)c3ccccc23)cc1 Show InChI InChI=1S/C29H38N2O2/c1-33-25-15-13-24(14-16-25)22-31-27-12-8-7-11-26(27)29(28(31)32)17-19-30(20-18-29)21-23-9-5-3-2-4-6-10-23/h7-8,11-16,23H,2-6,9-10,17-22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...				Bioorg Med Chem Lett 15: 5022-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.009 BindingDB Entry DOI: 10.7270/Q2RF5TKC
					More data for this Ligand-Target Pair