BDBM50173291 (5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)-(4'-methyl-biphenyl-4-yl)-methanone::CHEMBL424663

SMILES: Cc1ccc(cc1)-c1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12

InChI Key: InChIKey=NQUCSCZUVAWROC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50173291 ((5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...) Show SMILES Cc1ccc(cc1)-c1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12 Show InChI InChI=1S/C26H22N2O/c1-19-8-10-20(11-9-19)21-12-14-22(15-13-21)26(29)28-18-24-6-4-16-27(24)17-23-5-2-3-7-25(23)28/h2-16H,17-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]-AVP binding to human V2 receptor				Bioorg Med Chem Lett 15: 5003-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.007 BindingDB Entry DOI: 10.7270/Q2C828WH
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50173291 ((5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...) Show SMILES Cc1ccc(cc1)-c1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12 Show InChI InChI=1S/C26H22N2O/c1-19-8-10-20(11-9-19)21-12-14-22(15-13-21)26(29)28-18-24-6-4-16-27(24)17-23-5-2-3-7-25(23)28/h2-16H,17-18H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-AVP binding to human vasopressin V1a receptor				Bioorg Med Chem Lett 15: 5003-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.007 BindingDB Entry DOI: 10.7270/Q2C828WH
					More data for this Ligand-Target Pair