BDBM50173298 Biphenyl-4-yl-(3-dimethylaminomethyl-5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)-methanone::CHEMBL371721

SMILES: CN(C)Cc1ccc2CN(C(=O)c3ccc(cc3)-c3ccccc3)c3ccccc3Cn12

InChI Key: InChIKey=MUVJXVCECBEFIQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50173298 (Biphenyl-4-yl-(3-dimethylaminomethyl-5H,11H-benzo[...) Show SMILES CN(C)Cc1ccc2CN(C(=O)c3ccc(cc3)-c3ccccc3)c3ccccc3Cn12 Show InChI InChI=1S/C28H27N3O/c1-29(2)19-25-16-17-26-20-31(27-11-7-6-10-24(27)18-30(25)26)28(32)23-14-12-22(13-15-23)21-8-4-3-5-9-21/h3-17H,18-20H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-AVP binding to human vasopressin V1a receptor				Bioorg Med Chem Lett 15: 5003-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.007 BindingDB Entry DOI: 10.7270/Q2C828WH
					More data for this Ligand-Target Pair