BDBM50173378 CHEMBL198277::N-{1-[3-(4-Chloro-phenyl)-3-phenyl-propyl]-piperidin-4-yl}-N-ethyl-2-(4-methanesulfonyl-phenyl)-acetamide

SMILES: CCN(C1CCN(CCC(c2ccccc2)c2ccc(Cl)cc2)CC1)C(=O)Cc1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=ASZPWIAQUZJALQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50173378 (CHEMBL198277 | N-{1-[3-(4-Chloro-phenyl)-3-phenyl-...) Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccc(Cl)cc2)CC1)C(=O)Cc1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C31H37ClN2O3S/c1-3-34(31(35)23-24-9-15-29(16-10-24)38(2,36)37)28-17-20-33(21-18-28)22-19-30(25-7-5-4-6-8-25)26-11-13-27(32)14-12-26/h4-16,28,30H,3,17-23H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cells				Bioorg Med Chem Lett 15: 5012-5 (2005) Article DOI: 10.1016/j.bmcl.2005.08.014 BindingDB Entry DOI: 10.7270/Q23R0SFG
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