null

SMILES: FC1(F)Oc2ccc(CN3CCC(CC3)Nc3cc(=O)oc4ccc(Cl)cc34)cc2O1

InChI Key: InChIKey=KSHGPOSCFJFCQM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50173453 (6-Chloro-4-[1-(2,2-difluoro-benzo[1,3]dioxol-5-ylm...) Show SMILES FC1(F)Oc2ccc(CN3CCC(CC3)Nc3cc(=O)oc4ccc(Cl)cc34)cc2O1 Show InChI InChI=1S/C22H19ClF2N2O4/c23-14-2-4-18-16(10-14)17(11-21(28)29-18)26-15-5-7-27(8-6-15)12-13-1-3-19-20(9-13)31-22(24,25)30-19/h1-4,9-11,15,26H,5-8,12H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH				J Med Chem 48: 5888-91 (2005) Article DOI: 10.1021/jm050598r BindingDB Entry DOI: 10.7270/Q2QJ7GTV
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50173453 (6-Chloro-4-[1-(2,2-difluoro-benzo[1,3]dioxol-5-ylm...) Show SMILES FC1(F)Oc2ccc(CN3CCC(CC3)Nc3cc(=O)oc4ccc(Cl)cc34)cc2O1 Show InChI InChI=1S/C22H19ClF2N2O4/c23-14-2-4-18-16(10-14)17(11-21(28)29-18)26-15-5-7-27(8-6-15)12-13-1-3-19-20(9-13)31-22(24,25)30-19/h1-4,9-11,15,26H,5-8,12H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	581	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assay				J Med Chem 48: 5888-91 (2005) Article DOI: 10.1021/jm050598r BindingDB Entry DOI: 10.7270/Q2QJ7GTV
					More data for this Ligand-Target Pair