BDBM50173594 CHEMBL3809254
SMILES: Nc1cc(no1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1
InChI Key: InChIKey=NRPFQPPACYQGLQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50173594 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173594
(CHEMBL3809254)Show SMILES Nc1cc(no1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C17H13F3N4O2/c18-17(19,20)11-2-1-3-13(8-11)23-16(25)22-12-6-4-10(5-7-12)14-9-15(21)26-24-14/h1-9H,21H2,(H2,22,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
ACS Med Chem Lett 7: 363-7 (2016)
BindingDB Entry DOI: 10.7270/Q24J0H11 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173594
(CHEMBL3809254)Show SMILES Nc1cc(no1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C17H13F3N4O2/c18-17(19,20)11-2-1-3-13(8-11)23-16(25)22-12-6-4-10(5-7-12)14-9-15(21)26-24-14/h1-9H,21H2,(H2,22,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
ACS Med Chem Lett 7: 363-7 (2016)
BindingDB Entry DOI: 10.7270/Q24J0H11 |
More data for this Ligand-Target Pair | |