BDBM50173596 CHEMBL3809608

SMILES: CC(C)(C)C(=O)Nc1cc([nH]n1)-c1ccc(NC(=O)Nc2cc(on2)C(C)(C)C)cc1

InChI Key: InChIKey=XNKCXSVBIUSWQP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173596 (CHEMBL3809608) Show SMILES CC(C)(C)C(=O)Nc1cc([nH]n1)-c1ccc(NC(=O)Nc2cc(on2)C(C)(C)C)cc1 Show InChI InChI=1S/C22H28N6O3/c1-21(2,3)16-12-18(28-31-16)25-20(30)23-14-9-7-13(8-10-14)15-11-17(27-26-15)24-19(29)22(4,5)6/h7-12H,1-6H3,(H2,23,25,28,30)(H2,24,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse Baf3 cells				ACS Med Chem Lett 7: 363-7 (2016) BindingDB Entry DOI: 10.7270/Q24J0H11
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173596 (CHEMBL3809608) Show SMILES CC(C)(C)C(=O)Nc1cc([nH]n1)-c1ccc(NC(=O)Nc2cc(on2)C(C)(C)C)cc1 Show InChI InChI=1S/C22H28N6O3/c1-21(2,3)16-12-18(28-31-16)25-20(30)23-14-9-7-13(8-10-14)15-11-17(27-26-15)24-19(29)22(4,5)6/h7-12H,1-6H3,(H2,23,25,28,30)(H2,24,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin)				ACS Med Chem Lett 7: 363-7 (2016) BindingDB Entry DOI: 10.7270/Q24J0H11
					More data for this Ligand-Target Pair