BDBM50173597 CHEMBL3809588

SMILES: CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cc(NC(=O)C3CC3)n[nH]2)no1

InChI Key: InChIKey=KHFZBZKIEYHQSB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173597 (CHEMBL3809588) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cc(NC(=O)C3CC3)n[nH]2)no1 Show InChI InChI=1S/C21H24N6O3/c1-21(2,3)16-11-18(27-30-16)24-20(29)22-14-8-6-12(7-9-14)15-10-17(26-25-15)23-19(28)13-4-5-13/h6-11,13H,4-5H2,1-3H3,(H2,22,24,27,29)(H2,23,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse Baf3 cells				ACS Med Chem Lett 7: 363-7 (2016) BindingDB Entry DOI: 10.7270/Q24J0H11
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173597 (CHEMBL3809588) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cc(NC(=O)C3CC3)n[nH]2)no1 Show InChI InChI=1S/C21H24N6O3/c1-21(2,3)16-11-18(27-30-16)24-20(29)22-14-8-6-12(7-9-14)15-10-17(26-25-15)23-19(28)13-4-5-13/h6-11,13H,4-5H2,1-3H3,(H2,22,24,27,29)(H2,23,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin)				ACS Med Chem Lett 7: 363-7 (2016) BindingDB Entry DOI: 10.7270/Q24J0H11
					More data for this Ligand-Target Pair