BDBM50173598 CHEMBL3808728
SMILES: CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cc(NC(=O)C3CC3)on2)no1
InChI Key: InChIKey=ROWQYTIRUFMIIY-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50173598 (CHEMBL3808728) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse Baf3 cells | ACS Med Chem Lett 7: 363-7 (2016) BindingDB Entry DOI: 10.7270/Q24J0H11 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50173598 (CHEMBL3808728) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of KDR (unknown origin) | ACS Med Chem Lett 7: 363-7 (2016) BindingDB Entry DOI: 10.7270/Q24J0H11 | |||||||||||
More data for this Ligand-Target Pair |