BDBM50173604 CHEMBL3809895

SMILES: CC(C)(C)c1cc(NC(=O)Nc2ccc(Cc3cc(N)n[nH]3)cc2)no1

InChI Key: InChIKey=WJJDWJJQHOPEFV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173604 (CHEMBL3809895) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Cc3cc(N)n[nH]3)cc2)no1 Show InChI InChI=1S/C18H22N6O2/c1-18(2,3)14-10-16(24-26-14)21-17(25)20-12-6-4-11(5-7-12)8-13-9-15(19)23-22-13/h4-7,9-10H,8H2,1-3H3,(H3,19,22,23)(H2,20,21,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin)				ACS Med Chem Lett 7: 363-7 (2016) BindingDB Entry DOI: 10.7270/Q24J0H11
					More data for this Ligand-Target Pair