BDBM50173753 CHEMBL371912::[(3-Amino-phenylamino)-phosphono-methyl]-phosphonic acid

SMILES: Nc1cccc(NC(P(O)(O)=O)P(O)(O)=O)c1

InChI Key: InChIKey=ABEOTXVLVCXCDW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vacuolar-type proton translocating pyrophosphatase 1 (Trypanosoma brucei)	BDBM50173753 (CHEMBL371912 | [(3-Amino-phenylamino)-phosphono-me...) Show SMILES Nc1cccc(NC(P(O)(O)=O)P(O)(O)=O)c1 Show InChI InChI=1S/C7H12N2O6P2/c8-5-2-1-3-6(4-5)9-7(16(10,11)12)17(13,14)15/h1-4,7,9H,8H2,(H2,10,11,12)(H2,13,14,15)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coli				J Med Chem 48: 6128-39 (2005) Article DOI: 10.1021/jm058220g BindingDB Entry DOI: 10.7270/Q2F47PX2
					More data for this Ligand-Target Pair