BDBM50173809 3-[(E)-4-(3,4-Dimethoxy-phenyl)-4-(3-fluoro-5-trifluoromethyl-phenyl)-but-3-enyl]-oxazolidin-2-one::CHEMBL196121

SMILES: COc1ccc(cc1OC)C(=C/CCN1CCOC1=O)\c1cc(F)cc(c1)C(F)(F)F

InChI Key: InChIKey=AZMXYEMIXOVLEA-JJPRUIFNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50173809 (3-[(E)-4-(3,4-Dimethoxy-phenyl)-4-(3-fluoro-5-trif...) Show SMILES COc1ccc(cc1OC)C(=C/CCN1CCOC1=O)\c1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C22H21F4NO4/c1-29-19-6-5-14(12-20(19)30-2)18(4-3-7-27-8-9-31-21(27)28)15-10-16(22(24,25)26)13-17(23)11-15/h4-6,10-13H,3,7-9H2,1-2H3/b18-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of recombinant HIV-1 reverse transcriptase activity				J Med Chem 48: 6140-55 (2005) Article DOI: 10.1021/jm050452s BindingDB Entry DOI: 10.7270/Q2TB16F6
					More data for this Ligand-Target Pair