BDBM50173810 5-[(E)-1-(3,4-Dimethoxy-phenyl)-4-(2-oxo-oxazolidin-3-yl)-but-1-enyl]-2-methoxy-3-methyl-benzoic acid methyl ester::CHEMBL198551

SMILES: COC(=O)c1cc(cc(C)c1OC)C(=C/CCN1CCOC1=O)\c1ccc(OC)c(OC)c1

InChI Key: InChIKey=OIOGYJCBYVTLEG-GXHLCREISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173810   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50173810 (5-[(E)-1-(3,4-Dimethoxy-phenyl)-4-(2-oxo-oxazolidi...) Show SMILES COC(=O)c1cc(cc(C)c1OC)C(=C/CCN1CCOC1=O)\c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C25H29NO7/c1-16-13-18(14-20(23(16)31-4)24(27)32-5)19(7-6-10-26-11-12-33-25(26)28)17-8-9-21(29-2)22(15-17)30-3/h7-9,13-15H,6,10-12H2,1-5H3/b19-7-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of recombinant HIV-1 reverse transcriptase activity				J Med Chem 48: 6140-55 (2005) Article DOI: 10.1021/jm050452s BindingDB Entry DOI: 10.7270/Q2TB16F6
					More data for this Ligand-Target Pair