BDBM50174016 CHEMBL370220::N-(3-(6-(pyridin-4-ylmethyl)quinolin-8-yl)phenyl)benzenesulfonamide

SMILES: O=S(=O)(Nc1cccc(c1)-c1cc(Cc2ccncc2)cc2cccnc12)c1ccccc1

InChI Key: InChIKey=LZXLYACBALMEJP-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50174016 (CHEMBL370220 | N-(3-(6-(pyridin-4-ylmethyl)quinoli...) Show SMILES O=S(=O)(Nc1cccc(c1)-c1cc(Cc2ccncc2)cc2cccnc12)c1ccccc1 Show InChI InChI=1S/C27H21N3O2S/c31-33(32,25-9-2-1-3-10-25)30-24-8-4-6-22(19-24)26-18-21(16-20-11-14-28-15-12-20)17-23-7-5-13-29-27(23)26/h1-15,17-19,30H,16H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against PDE4D				Bioorg Med Chem Lett 15: 5241-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50174016 (CHEMBL370220 | N-(3-(6-(pyridin-4-ylmethyl)quinoli...) Show SMILES O=S(=O)(Nc1cccc(c1)-c1cc(Cc2ccncc2)cc2cccnc12)c1ccccc1 Show InChI InChI=1S/C27H21N3O2S/c31-33(32,25-9-2-1-3-10-25)30-24-8-4-6-22(19-24)26-18-21(16-20-11-14-28-15-12-20)17-23-7-5-13-29-27(23)26/h1-15,17-19,30H,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against PDE4B				Bioorg Med Chem Lett 15: 5241-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50174016 (CHEMBL370220 | N-(3-(6-(pyridin-4-ylmethyl)quinoli...) Show SMILES O=S(=O)(Nc1cccc(c1)-c1cc(Cc2ccncc2)cc2cccnc12)c1ccccc1 Show InChI InChI=1S/C27H21N3O2S/c31-33(32,25-9-2-1-3-10-25)30-24-8-4-6-22(19-24)26-18-21(16-20-11-14-28-15-12-20)17-23-7-5-13-29-27(23)26/h1-15,17-19,30H,16H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against PDE4A				Bioorg Med Chem Lett 15: 5241-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Homo sapiens (Human))	BDBM50174016 (CHEMBL370220 | N-(3-(6-(pyridin-4-ylmethyl)quinoli...) Show SMILES O=S(=O)(Nc1cccc(c1)-c1cc(Cc2ccncc2)cc2cccnc12)c1ccccc1 Show InChI InChI=1S/C27H21N3O2S/c31-33(32,25-9-2-1-3-10-25)30-24-8-4-6-22(19-24)26-18-21(16-20-11-14-28-15-12-20)17-23-7-5-13-29-27(23)26/h1-15,17-19,30H,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	11.9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against PDE4C				Bioorg Med Chem Lett 15: 5241-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG
					More data for this Ligand-Target Pair