Found 8 hits for monomerid = 50174017 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
3',5'-cyclic phosphodiesterase
(Homo sapiens (Human)) | BDBM50174017
(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)Show InChI InChI=1S/C22H18N2O/c1-25-20-6-2-4-18(15-20)21-14-17(12-16-7-10-23-11-8-16)13-19-5-3-9-24-22(19)21/h2-11,13-15H,12H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Inhibition of human PDE4C |
Bioorg Med Chem Lett 20: 5502-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.076 BindingDB Entry DOI: 10.7270/Q2K35TVZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50174017
(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)Show InChI InChI=1S/C22H18N2O/c1-25-20-6-2-4-18(15-20)21-14-17(12-16-7-10-23-11-8-16)13-19-5-3-9-24-22(19)21/h2-11,13-15H,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Inhibition of human PDE4D |
Bioorg Med Chem Lett 20: 5502-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.076 BindingDB Entry DOI: 10.7270/Q2K35TVZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
(Homo sapiens (Human)) | BDBM50174017
(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)Show InChI InChI=1S/C22H18N2O/c1-25-20-6-2-4-18(15-20)21-14-17(12-16-7-10-23-11-8-16)13-19-5-3-9-24-22(19)21/h2-11,13-15H,12H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Inhibition of human PDE4A |
Bioorg Med Chem Lett 20: 5502-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.076 BindingDB Entry DOI: 10.7270/Q2K35TVZ |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50174017
(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)Show InChI InChI=1S/C22H18N2O/c1-25-20-6-2-4-18(15-20)21-14-17(12-16-7-10-23-11-8-16)13-19-5-3-9-24-22(19)21/h2-11,13-15H,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Inhibitory activity against PDE4D |
Bioorg Med Chem Lett 15: 5241-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
(Homo sapiens (Human)) | BDBM50174017
(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)Show InChI InChI=1S/C22H18N2O/c1-25-20-6-2-4-18(15-20)21-14-17(12-16-7-10-23-11-8-16)13-19-5-3-9-24-22(19)21/h2-11,13-15H,12H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Inhibitory activity against PDE4A |
Bioorg Med Chem Lett 15: 5241-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG |
More data for this Ligand-Target Pair | |
3',5'-cyclic phosphodiesterase
(Homo sapiens (Human)) | BDBM50174017
(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)Show InChI InChI=1S/C22H18N2O/c1-25-20-6-2-4-18(15-20)21-14-17(12-16-7-10-23-11-8-16)13-19-5-3-9-24-22(19)21/h2-11,13-15H,12H2,1H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Inhibitory activity against PDE4B |
Bioorg Med Chem Lett 15: 5241-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG |
More data for this Ligand-Target Pair | |
3',5'-cyclic phosphodiesterase
(Homo sapiens (Human)) | BDBM50174017
(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)Show InChI InChI=1S/C22H18N2O/c1-25-20-6-2-4-18(15-20)21-14-17(12-16-7-10-23-11-8-16)13-19-5-3-9-24-22(19)21/h2-11,13-15H,12H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Inhibitory activity against PDE4C |
Bioorg Med Chem Lett 15: 5241-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG |
More data for this Ligand-Target Pair | |
3',5'-cyclic phosphodiesterase
(Homo sapiens (Human)) | BDBM50174017
(8-(3-(2-(3-methylcyclopenta-1,3-dienyl)-2-(4-(meth...)Show InChI InChI=1S/C22H18N2O/c1-25-20-6-2-4-18(15-20)21-14-17(12-16-7-10-23-11-8-16)13-19-5-3-9-24-22(19)21/h2-11,13-15H,12H2,1H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Inhibition of human PDE4B |
Bioorg Med Chem Lett 20: 5502-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.076 BindingDB Entry DOI: 10.7270/Q2K35TVZ |
More data for this Ligand-Target Pair | |