Found 3 hits for monomerid = 50174042 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50174042
(CHEMBL3809650)Show SMILES CN(C)C[C@H]1CCc2cc(ccc2[C@]1(O)c1cccc(O)c1)-c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C25H25Cl2NO2/c1-28(2)15-20-9-6-18-12-16(17-8-11-23(26)24(27)13-17)7-10-22(18)25(20,30)19-4-3-5-21(29)14-19/h3-5,7-8,10-14,20,29-30H,6,9,15H2,1-2H3/t20-,25+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University
Curated by ChEMBL
| Assay Description Displacement of [3H]U69593 from human KOR expressed in CHO cell membranes after 60 mins |
ACS Med Chem Lett 7: 391-6 (2016)
Article DOI: 10.1021/acsmedchemlett.5b00423 BindingDB Entry DOI: 10.7270/Q2R78H4W |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50174042
(CHEMBL3809650)Show SMILES CN(C)C[C@H]1CCc2cc(ccc2[C@]1(O)c1cccc(O)c1)-c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C25H25Cl2NO2/c1-28(2)15-20-9-6-18-12-16(17-8-11-23(26)24(27)13-17)7-10-22(18)25(20,30)19-4-3-5-21(29)14-19/h3-5,7-8,10-14,20,29-30H,6,9,15H2,1-2H3/t20-,25+/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University
Curated by ChEMBL
| Assay Description Displacement of [3H]DAMGO from human MOR expressed in CHO cell membranes after 60 mins |
ACS Med Chem Lett 7: 391-6 (2016)
Article DOI: 10.1021/acsmedchemlett.5b00423 BindingDB Entry DOI: 10.7270/Q2R78H4W |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50174042
(CHEMBL3809650)Show SMILES CN(C)C[C@H]1CCc2cc(ccc2[C@]1(O)c1cccc(O)c1)-c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C25H25Cl2NO2/c1-28(2)15-20-9-6-18-12-16(17-8-11-23(26)24(27)13-17)7-10-22(18)25(20,30)19-4-3-5-21(29)14-19/h3-5,7-8,10-14,20,29-30H,6,9,15H2,1-2H3/t20-,25+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University
Curated by ChEMBL
| Assay Description Displacement of [3H]DPDPE from human DOR expressed in CHO cell membranes after 60 mins |
ACS Med Chem Lett 7: 391-6 (2016)
Article DOI: 10.1021/acsmedchemlett.5b00423 BindingDB Entry DOI: 10.7270/Q2R78H4W |
More data for this Ligand-Target Pair | |