BDBM50174240 CHEMBL197278::N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenylacetamido)methyl)cyclohexyl)piperazin-1-yl)propan-2-yl)indoline-2-carboxamide

SMILES: Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3N2)C(=O)N2CCN(CC2)C2(CNC(=O)Cc3ccccc3)CCCCC2)cc1

InChI Key: InChIKey=MKJINNZJGZZYPA-ZHZZGXISSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50174240 (CHEMBL197278 | N-((R)-3-(4-chlorophenyl)-1-oxo-1-(...) Show SMILES Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3N2)C(=O)N2CCN(CC2)C2(CNC(=O)Cc3ccccc3)CCCCC2)cc1 Show InChI InChI=1S/C37H44ClN5O3/c38-30-15-13-28(14-16-30)23-33(41-35(45)32-25-29-11-5-6-12-31(29)40-32)36(46)42-19-21-43(22-20-42)37(17-7-2-8-18-37)26-39-34(44)24-27-9-3-1-4-10-27/h1,3-6,9-16,32-33,40H,2,7-8,17-26H2,(H,39,44)(H,41,45)/t32?,33-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 15: 5237-40 (2005) Article DOI: 10.1016/j.bmcl.2005.08.061 BindingDB Entry DOI: 10.7270/Q2794476
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50174240 (CHEMBL197278 | N-((R)-3-(4-chlorophenyl)-1-oxo-1-(...) Show SMILES Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3N2)C(=O)N2CCN(CC2)C2(CNC(=O)Cc3ccccc3)CCCCC2)cc1 Show InChI InChI=1S/C37H44ClN5O3/c38-30-15-13-28(14-16-30)23-33(41-35(45)32-25-29-11-5-6-12-31(29)40-32)36(46)42-19-21-43(22-20-42)37(17-7-2-8-18-37)26-39-34(44)24-27-9-3-1-4-10-27/h1,3-6,9-16,32-33,40H,2,7-8,17-26H2,(H,39,44)(H,41,45)/t32?,33-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description cAMP stimulation in HEK293 cells transfected with human MC4R				Bioorg Med Chem Lett 15: 5237-40 (2005) Article DOI: 10.1016/j.bmcl.2005.08.061 BindingDB Entry DOI: 10.7270/Q2794476
					More data for this Ligand-Target Pair