BDBM50174246 2-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenylacetamido)methyl)cyclohexyl)piperazin-1-yl)propan-2-yl)-3-phenylpropanamide::CHEMBL197328

SMILES: NC(Cc1ccccc1)C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNC(=O)Cc2ccccc2)CCCCC1

InChI Key: InChIKey=NKTQNWJIUFSESY-ZHZZGXISSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50174246 (2-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...) Show SMILES NC(Cc1ccccc1)C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNC(=O)Cc2ccccc2)CCCCC1 Show InChI InChI=1S/C37H46ClN5O3/c38-31-16-14-30(15-17-31)25-33(41-35(45)32(39)24-28-10-4-1-5-11-28)36(46)42-20-22-43(23-21-42)37(18-8-3-9-19-37)27-40-34(44)26-29-12-6-2-7-13-29/h1-2,4-7,10-17,32-33H,3,8-9,18-27,39H2,(H,40,44)(H,41,45)/t32?,33-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 15: 5237-40 (2005) Article DOI: 10.1016/j.bmcl.2005.08.061 BindingDB Entry DOI: 10.7270/Q2794476
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50174246 (2-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...) Show SMILES NC(Cc1ccccc1)C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNC(=O)Cc2ccccc2)CCCCC1 Show InChI InChI=1S/C37H46ClN5O3/c38-31-16-14-30(15-17-31)25-33(41-35(45)32(39)24-28-10-4-1-5-11-28)36(46)42-20-22-43(23-21-42)37(18-8-3-9-19-37)27-40-34(44)26-29-12-6-2-7-13-29/h1-2,4-7,10-17,32-33H,3,8-9,18-27,39H2,(H,40,44)(H,41,45)/t32?,33-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description cAMP stimulation in HEK293 cells transfected with human MC4R				Bioorg Med Chem Lett 15: 5237-40 (2005) Article DOI: 10.1016/j.bmcl.2005.08.061 BindingDB Entry DOI: 10.7270/Q2794476
					More data for this Ligand-Target Pair