BDBM50174267 CHEMBL198797::N4,N6-dimethyl-1-(phenylsulfonyl)-1H-indole-4,6-diamine

SMILES: CNc1cc(NC)c2ccn(c2c1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=YMOXFYZRVOPDDY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50174267 (CHEMBL198797 | N4,N6-dimethyl-1-(phenylsulfonyl)-1...) Show SMILES CNc1cc(NC)c2ccn(c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C16H17N3O2S/c1-17-12-10-15(18-2)14-8-9-19(16(14)11-12)22(20,21)13-6-4-3-5-7-13/h3-11,17-18H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 15: 5298-302 (2005) Article DOI: 10.1016/j.bmcl.2005.08.059 BindingDB Entry DOI: 10.7270/Q2ZW1KGZ
					More data for this Ligand-Target Pair