BDBM50174289 3-(4-(3-(cyclopropylmethyl)-1,2,4-oxadiazol-5-yl)bicyclo[2.2.2]octan-1-yl)-5,6,7,8,9,10-hexahydro-[1,2,4]triazolo[4,3-a]azocine::CHEMBL200365

SMILES: C(C1CC1)c1noc(n1)C12CCC(CC1)(CC2)c1nnc2CCCCCCn12

InChI Key: InChIKey=BXRXOYXFCQSGFT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2) (Mus musculus (mouse))	BDBM50174289 (3-(4-(3-(cyclopropylmethyl)-1,2,4-oxadiazol-5-yl)b...) Show SMILES C(C1CC1)c1noc(n1)C12CCC(CC1)(CC2)c1nnc2CCCCCCn12 Show InChI InChI=1S/C22H31N5O/c1-2-4-14-27-18(5-3-1)24-25-19(27)21-8-11-22(12-9-21,13-10-21)20-23-17(26-28-20)15-16-6-7-16/h16H,1-15H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibitory activity against mouse 11beta-HSD2				Bioorg Med Chem Lett 15: 5266-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.052 BindingDB Entry DOI: 10.7270/Q2QC031M
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50174289 (3-(4-(3-(cyclopropylmethyl)-1,2,4-oxadiazol-5-yl)b...) Show SMILES C(C1CC1)c1noc(n1)C12CCC(CC1)(CC2)c1nnc2CCCCCCn12 Show InChI InChI=1S/C22H31N5O/c1-2-4-14-27-18(5-3-1)24-25-19(27)21-8-11-22(12-9-21,13-10-21)20-23-17(26-28-20)15-16-6-7-16/h16H,1-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibitory activity against human 11beta-HSD1				Bioorg Med Chem Lett 15: 5266-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.052 BindingDB Entry DOI: 10.7270/Q2QC031M
					More data for this Ligand-Target Pair