null

SMILES: Cn1cc(cc1C=CC(=O)CC(=O)C(O)=O)C(=O)c1ccc(F)cc1

InChI Key: InChIKey=MWHNLHLQSBEVQO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50174457 ((Z)-6-[4-(4-Fluoro-benzoyl)-1-methyl-1H-pyrrol-2-y...) Show SMILES Cn1cc(cc1C=CC(=O)CC(=O)C(O)=O)C(=O)c1ccc(F)cc1 |w:7.8| Show InChI InChI=1S/C18H14FNO5/c1-20-10-12(17(23)11-2-4-13(19)5-3-11)8-14(20)6-7-15(21)9-16(22)18(24)25/h2-8,10H,9H2,1H3,(H,24,25)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	7.5	n/a
University of Rome La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)				J Med Chem 48: 6304-14 (2005) Article DOI: 10.1021/jm0504454 BindingDB Entry DOI: 10.7270/Q2T43SNM
					More data for this Ligand-Target Pair