BindingDB PrimarySearch

BDBM50174611 CHEMBL437275::HYNIC Conjugate

SMILES: CC(C)(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(O)(=O)=O)NC(=O)[C@H](CS(O)(=O)=O)NC(=O)[C@H](CS(O)(=O)=O)NC(=O)[C@H](CS(O)(=O)=O)NC(=O)CC[C@H](NC(=O)c1ccc(N=NCc2ccccc2)nc1)C(=O)N[C@@H](CS(O)(=O)=O)C(=O)N[C@@H](CS(O)(=O)=O)C(=O)N[C@@H](CS(O)(=O)=O)C(=O)N[C@@H](CS(O)(=O)=O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1

InChI Key: InChIKey=KXBKBOJKESCAII-GNCPCNMMSA-N

Data: 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174611
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50174611 (CHEMBL437275 \| HYNIC Conjugate) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	7.2	n/a
Bristol-Myers Squibb Medical Imaging Curated by ChEMBL					Assay Description Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 h at 37 deg...				J Med Chem 48: 6442-53 (2005) Article DOI: 10.1021/jm050383h BindingDB Entry DOI: 10.7270/Q2959H33
Bristol-Myers Squibb Medical Imaging Curated by ChEMBL					More data for this Ligand-Target Pair