BDBM50174725 CHEMBL3808983

SMILES: Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CC[C@H](F)C3)c2c1C

InChI Key: InChIKey=SCOIDAIWNQYJDD-AWEZNQCLSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174725 (CHEMBL3808983) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CC[C@H](F)C3)c2c1C |r| Show InChI InChI=1S/C18H23FN4OS/c1-11-12(2)25-17-15(11)16(20-10-21-17)22-6-3-13(4-7-22)18(24)23-8-5-14(19)9-23/h10,13-14H,3-9H2,1-2H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	977	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174725 (CHEMBL3808983) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CC[C@H](F)C3)c2c1C |r| Show InChI InChI=1S/C18H23FN4OS/c1-11-12(2)25-17-15(11)16(20-10-21-17)22-6-3-13(4-7-22)18(24)23-8-5-14(19)9-23/h10,13-14H,3-9H2,1-2H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	970	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair