BDBM50174831 CHEMBL196864::N-(3'-cyano-biphenyl-4-ylmethyl)-N-[(3,5-dichloro-phenylcarbamoyl)-methyl]-2-((S)-3-hydroxy-pyrrolidin-1-yl)-acetamide

SMILES: O[C@H]1CCN(CC(=O)N(CC(=O)Nc2cc(Cl)cc(Cl)c2)Cc2ccc(cc2)-c2cccc(c2)C#N)C1

InChI Key: InChIKey=SXVNAXRSGNGEAG-SANMLTNESA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50174831 (CHEMBL196864 | N-(3'-cyano-biphenyl-4-ylmethyl)-N-...) Show SMILES O[C@H]1CCN(CC(=O)N(CC(=O)Nc2cc(Cl)cc(Cl)c2)Cc2ccc(cc2)-c2cccc(c2)C#N)C1 Show InChI InChI=1S/C28H26Cl2N4O3/c29-23-11-24(30)13-25(12-23)32-27(36)17-34(28(37)18-33-9-8-26(35)16-33)15-19-4-6-21(7-5-19)22-3-1-2-20(10-22)14-31/h1-7,10-13,26,35H,8-9,15-18H2,(H,32,36)/t26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor				Bioorg Med Chem Lett 15: 5234-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.043 BindingDB Entry DOI: 10.7270/Q24F1Q80
					More data for this Ligand-Target Pair
GPR145 (Homo sapiens (Human))	BDBM50174831 (CHEMBL196864 | N-(3'-cyano-biphenyl-4-ylmethyl)-N-...) Show SMILES O[C@H]1CCN(CC(=O)N(CC(=O)Nc2cc(Cl)cc(Cl)c2)Cc2ccc(cc2)-c2cccc(c2)C#N)C1 Show InChI InChI=1S/C28H26Cl2N4O3/c29-23-11-24(30)13-25(12-23)32-27(36)17-34(28(37)18-33-9-8-26(35)16-33)15-19-4-6-21(7-5-19)22-3-1-2-20(10-22)14-31/h1-7,10-13,26,35H,8-9,15-18H2,(H,32,36)/t26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity against human MCH2 receptor				Bioorg Med Chem Lett 15: 5234-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.043 BindingDB Entry DOI: 10.7270/Q24F1Q80
					More data for this Ligand-Target Pair