BDBM50174843 3-(9H-fluoren-9-yl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene::3-(9H-fluoren-9-yl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene::CHEMBL201223

SMILES: CN1C2CCC1C=C(C2)C1c2ccccc2-c2ccccc12

InChI Key: InChIKey=OAASRUWEEIXAQF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174843   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50174843 (3-(9H-fluoren-9-yl)-8-methyl-8-aza-bicyclo[3.2.1]o...) Show SMILES CN1C2CCC1C=C(C2)C1c2ccccc2-c2ccccc12 |c:7,THB:9:7:1:3.4| Show InChI InChI=1S/C21H21N/c1-22-15-10-11-16(22)13-14(12-15)21-19-8-4-2-6-17(19)18-7-3-5-9-20(18)21/h2-9,12,15-16,21H,10-11,13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]Citalopram from human SERT				Bioorg Med Chem Lett 15: 5488-93 (2005) Article DOI: 10.1016/j.bmcl.2005.08.082 BindingDB Entry DOI: 10.7270/Q20P0ZJ8
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50174843 (3-(9H-fluoren-9-yl)-8-methyl-8-aza-bicyclo[3.2.1]o...) Show SMILES CN1C2CCC1C=C(C2)C1c2ccccc2-c2ccccc12 |c:7,THB:9:7:1:3.4| Show InChI InChI=1S/C21H21N/c1-22-15-10-11-16(22)13-14(12-15)21-19-8-4-2-6-17(19)18-7-3-5-9-20(18)21/h2-9,12,15-16,21H,10-11,13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from human DAT				Bioorg Med Chem Lett 15: 5488-93 (2005) Article DOI: 10.1016/j.bmcl.2005.08.082 BindingDB Entry DOI: 10.7270/Q20P0ZJ8
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50174843 (3-(9H-fluoren-9-yl)-8-methyl-8-aza-bicyclo[3.2.1]o...) Show SMILES CN1C2CCC1C=C(C2)C1c2ccccc2-c2ccccc12 |c:7,THB:9:7:1:3.4| Show InChI InChI=1S/C21H21N/c1-22-15-10-11-16(22)13-14(12-15)21-19-8-4-2-6-17(19)18-7-3-5-9-20(18)21/h2-9,12,15-16,21H,10-11,13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]Nisoxetine from human NET				Bioorg Med Chem Lett 15: 5488-93 (2005) Article DOI: 10.1016/j.bmcl.2005.08.082 BindingDB Entry DOI: 10.7270/Q20P0ZJ8
					More data for this Ligand-Target Pair