BDBM50174869 CHEMBL409588::X3-Apc-DPhe-Arg-Trp-Z8-NH2

SMILES: NC(N)=NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@]1(CC[C@@H](CC1)c1ccccc1)NC(=O)Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cccc(c1)C(N)=O

InChI Key: InChIKey=CRPXKCYZZGISFW-KNFSONTISA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50174869 (CHEMBL409588 | X3-Apc-DPhe-Arg-Trp-Z8-NH2) Show SMILES NC(N)=NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@]1(CC[C@@H](CC1)c1ccccc1)NC(=O)Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cccc(c1)C(N)=O |wU:7.7,25.29,11.19,22.36,wD:47.50,22.22,(16.88,-28.19,;15.54,-28.96,;14.2,-28.19,;15.54,-30.51,;14.2,-31.28,;14.2,-32.82,;12.86,-33.6,;12.86,-35.15,;11.52,-35.92,;10.18,-35.15,;10.18,-33.6,;8.85,-35.92,;8.85,-37.46,;10.18,-38.24,;10.17,-39.79,;11.51,-40.55,;12.85,-39.78,;12.84,-38.23,;11.5,-37.46,;7.51,-35.15,;6.17,-35.92,;6.17,-37.46,;4.83,-35.15,;6.17,-34.38,;6.17,-32.85,;4.84,-32.07,;3.51,-32.84,;3.5,-34.38,;4.85,-30.54,;6.19,-29.78,;6.19,-28.24,;4.86,-27.47,;3.52,-28.24,;3.53,-29.77,;3.49,-35.92,;2.15,-35.15,;2.15,-33.6,;.82,-35.92,;-.52,-35.15,;-.51,-33.61,;-1.84,-32.85,;-3.17,-33.62,;-3.17,-35.16,;-1.83,-35.92,;14.2,-35.92,;14.2,-37.46,;15.54,-35.15,;16.88,-35.92,;16.88,-37.46,;18.21,-38.24,;19.56,-37.45,;20.66,-38.75,;19.9,-40.09,;20.37,-41.55,;19.34,-42.7,;17.82,-42.38,;17.35,-40.91,;18.38,-39.77,;18.21,-35.15,;18.21,-33.6,;19.55,-35.92,;20.88,-35.14,;22.22,-35.91,;22.21,-37.45,;23.54,-38.21,;24.88,-37.44,;24.87,-35.89,;23.53,-35.14,;26.19,-35.12,;27.53,-35.88,;26.18,-33.58,)| Show InChI InChI=1S/C55H62N10O6/c56-49(67)41-21-12-18-38(30-41)34-61-50(68)47(33-42-35-60-44-23-11-10-22-43(42)44)63-51(69)45(24-13-29-59-54(57)58)62-52(70)46(31-36-14-4-1-5-15-36)64-53(71)55(65-48(66)32-37-16-6-2-7-17-37)27-25-40(26-28-55)39-19-8-3-9-20-39/h1-12,14-23,30,35,40,45-47,60H,13,24-29,31-34H2,(H2,56,67)(H,61,68)(H,62,70)(H,63,69)(H,64,71)(H,65,66)(H4,57,58,59)/t40-,45-,46+,47-,55+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Agonist activity in HEK293 cells transfected with human MC4R by cAMP accumulation				Bioorg Med Chem Lett 15: 5504-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.083 BindingDB Entry DOI: 10.7270/Q2MC8ZK7
					More data for this Ligand-Target Pair