BDBM50174871 CHEMBL372201::X1-Apc-DPhe-Arg-Trp-Z10-NH2

SMILES: CCCC(=O)N[C@@]1(CC[C@@H](CC1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccc(cc1)C(N)=O

InChI Key: InChIKey=GWGICRRMJNPTLW-XQASKMHVSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174871   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50174871 (CHEMBL372201 | X1-Apc-DPhe-Arg-Trp-Z10-NH2) Show SMILES CCCC(=O)N[C@@]1(CC[C@@H](CC1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccc(cc1)C(N)=O |wU:32.34,9.12,21.22,6.5,wD:6.19,43.45,(-1.97,-35.98,;-.64,-35.21,;.69,-35.98,;2.02,-35.21,;2.02,-33.66,;3.36,-35.98,;4.7,-35.21,;6.04,-34.44,;6.04,-32.91,;4.71,-32.14,;3.38,-32.9,;3.37,-34.44,;4.72,-30.61,;6.06,-29.85,;6.06,-28.31,;4.73,-27.54,;3.4,-28.31,;3.4,-29.84,;6.03,-35.98,;6.03,-37.52,;7.37,-35.21,;8.71,-35.98,;8.71,-37.52,;10.04,-38.3,;10.03,-39.84,;11.37,-40.61,;12.71,-39.84,;12.7,-38.29,;11.37,-37.52,;10.04,-35.21,;10.04,-33.66,;11.38,-35.98,;12.72,-35.21,;12.72,-33.66,;14.05,-32.89,;14.05,-31.34,;15.39,-30.58,;15.39,-29.03,;16.73,-28.26,;14.05,-28.26,;14.05,-35.98,;14.05,-37.52,;15.39,-35.21,;16.73,-35.98,;16.73,-37.52,;18.07,-38.3,;19.41,-37.51,;20.52,-38.81,;19.75,-40.15,;20.22,-41.61,;19.19,-42.76,;17.67,-42.44,;17.2,-40.97,;18.24,-39.82,;18.07,-35.21,;18.07,-33.66,;19.41,-35.98,;20.73,-35.2,;22.07,-35.97,;22.06,-37.51,;23.39,-38.27,;24.72,-37.5,;24.71,-35.96,;23.38,-35.2,;26.05,-38.26,;27.38,-37.49,;26.06,-39.8,)| Show InChI InChI=1S/C51H62N10O6/c1-2-12-44(62)61-51(26-24-36(25-27-51)35-15-7-4-8-16-35)49(67)60-42(29-33-13-5-3-6-14-33)48(66)58-41(19-11-28-55-50(53)54)47(65)59-43(30-38-32-56-40-18-10-9-17-39(38)40)46(64)57-31-34-20-22-37(23-21-34)45(52)63/h3-10,13-18,20-23,32,36,41-43,56H,2,11-12,19,24-31H2,1H3,(H2,52,63)(H,57,64)(H,58,66)(H,59,65)(H,60,67)(H,61,62)(H4,53,54,55)/t36-,41-,42+,43-,51+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Agonist activity in HEK293 cells transfected with human MC4R by cAMP accumulation				Bioorg Med Chem Lett 15: 5504-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.083 BindingDB Entry DOI: 10.7270/Q2MC8ZK7
					More data for this Ligand-Target Pair