BDBM50174872 Bu-Apc-DPhe-Arg-2-Nal-Z9-NH2::CHEMBL200668

SMILES: CCCC(=O)N[C@@]1(CC[C@@H](CC1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)Nc1ccccc1C(N)=O

InChI Key: InChIKey=RTQSBEJKQYUGOX-VQJLCFANSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50174872 (Bu-Apc-DPhe-Arg-2-Nal-Z9-NH2 | CHEMBL200668) Show SMILES CCCC(=O)N[C@@]1(CC[C@@H](CC1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)Nc1ccccc1C(N)=O |wU:32.34,9.12,6.5,21.22,wD:6.19,(-8.1,-31.02,;-6.75,-30.25,;-5.44,-31.03,;-4.09,-30.25,;-4.09,-28.72,;-2.76,-31.03,;-1.42,-30.26,;-.08,-29.5,;-.08,-27.97,;-1.4,-27.19,;-2.74,-27.96,;-2.75,-29.5,;-1.4,-25.67,;-.06,-24.9,;-.06,-23.37,;-1.38,-22.59,;-2.72,-23.36,;-2.72,-24.9,;-.09,-31.03,;-.09,-32.57,;1.26,-30.25,;2.59,-31.03,;2.59,-32.57,;3.92,-33.35,;3.91,-34.89,;5.24,-35.65,;6.59,-34.89,;6.58,-33.34,;5.25,-32.57,;3.92,-30.25,;3.92,-28.72,;5.25,-31.03,;6.59,-30.25,;6.59,-28.72,;7.93,-27.94,;7.93,-26.4,;9.27,-25.63,;9.27,-24.09,;10.6,-23.31,;7.93,-23.31,;7.93,-31.03,;7.93,-32.57,;9.27,-30.25,;10.6,-31.03,;10.6,-32.57,;11.94,-33.35,;13.27,-32.57,;14.6,-33.35,;14.61,-34.89,;15.94,-35.67,;15.93,-37.21,;14.59,-37.98,;13.25,-37.21,;13.26,-35.66,;11.93,-34.89,;11.94,-30.25,;11.94,-28.72,;13.27,-31.03,;14.61,-30.26,;14.6,-28.73,;15.93,-27.95,;17.27,-28.73,;17.27,-30.27,;15.94,-31.04,;15.93,-32.57,;17.41,-32.98,;15.15,-33.9,)| Show InChI InChI=1S/C52H61N9O6/c1-2-14-45(62)61-52(28-26-38(27-29-52)36-17-7-4-8-18-36)50(67)60-44(32-34-15-5-3-6-16-34)49(66)58-42(23-13-30-56-51(54)55)47(64)59-43(33-35-24-25-37-19-9-10-20-39(37)31-35)48(65)57-41-22-12-11-21-40(41)46(53)63/h3-12,15-22,24-25,31,38,42-44H,2,13-14,23,26-30,32-33H2,1H3,(H2,53,63)(H,57,65)(H,58,66)(H,59,64)(H,60,67)(H,61,62)(H4,54,55,56)/t38-,42-,43?,44+,52+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Agonist activity in HEK293 cells transfected with human MC4R by cAMP accumulation				Bioorg Med Chem Lett 15: 5504-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.083 BindingDB Entry DOI: 10.7270/Q2MC8ZK7
					More data for this Ligand-Target Pair