BDBM50174875 CHEMBL414670::X2-5-BrAtc-DPhe-Arg-Trp-Z9-NH2

SMILES: CCCCNC(=O)NC1(CCc2c(Br)cccc2C1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccccc1C(N)=O

InChI Key: InChIKey=HZCVBVQHKXQRDW-VKXCKUKQSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50174875 (CHEMBL414670 | X2-5-BrAtc-DPhe-Arg-Trp-Z9-NH2) Show SMILES CCCCNC(=O)NC1(CCc2c(Br)cccc2C1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccccc1C(N)=O |wU:33.35,22.23,wD:44.46,(-12.69,-41.5,;-11.35,-40.73,;-10.02,-41.49,;-8.68,-40.73,;-7.36,-41.49,;-6.03,-40.72,;-6.03,-39.17,;-4.69,-41.49,;-3.34,-40.72,;-2.01,-39.95,;-2,-38.43,;-3.33,-37.65,;-3.34,-36.12,;-2,-35.37,;-4.66,-35.36,;-5.99,-36.13,;-5.98,-37.65,;-4.67,-38.41,;-4.67,-39.96,;-2.01,-41.49,;-2.01,-43.03,;-.68,-40.72,;.67,-41.49,;.67,-43.03,;1.99,-43.81,;1.98,-45.35,;3.32,-46.12,;4.66,-45.35,;4.66,-43.81,;3.32,-43.03,;1.99,-40.72,;1.99,-39.17,;3.33,-41.49,;4.67,-40.72,;4.67,-39.17,;6,-38.41,;6,-36.86,;7.35,-36.1,;7.35,-34.55,;8.68,-33.77,;6,-33.77,;6,-41.49,;6,-43.03,;7.35,-40.72,;8.68,-41.49,;8.68,-43.03,;10.02,-43.81,;11.36,-43.03,;12.46,-44.32,;11.69,-45.66,;12.17,-47.12,;11.14,-48.27,;9.63,-47.95,;9.15,-46.48,;10.19,-45.34,;10.02,-40.72,;10.02,-39.17,;11.36,-41.49,;12.68,-40.72,;13.43,-42.06,;14.96,-42.08,;15.74,-40.75,;14.98,-39.41,;13.45,-39.4,;12.69,-38.07,;13.47,-36.74,;11.16,-38.06,)| Show InChI InChI=1S/C49H58BrN11O6/c1-2-3-24-55-48(67)61-49(23-22-33-31(28-49)15-11-18-36(33)50)46(66)60-40(26-30-13-5-4-6-14-30)44(64)58-39(21-12-25-54-47(52)53)43(63)59-41(27-32-29-56-37-19-9-7-16-34(32)37)45(65)57-38-20-10-8-17-35(38)42(51)62/h4-11,13-20,29,39-41,56H,2-3,12,21-28H2,1H3,(H2,51,62)(H,57,65)(H,58,64)(H,59,63)(H,60,66)(H4,52,53,54)(H2,55,61,67)/t39-,40+,41-,49?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Agonist activity in HEK293 cells transfected with human MC4R by cAMP accumulation				Bioorg Med Chem Lett 15: 5504-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.083 BindingDB Entry DOI: 10.7270/Q2MC8ZK7
					More data for this Ligand-Target Pair