BDBM50175284 CHEMBL3808554
SMILES: Cl.CCCCCCCCCCCCc1ccc(cc1)-c1nc(no1)C1(CC1)C(N)=N
InChI Key: InChIKey=CIOCICQCGJPRBD-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine kinase 1 (SPHK1) (Homo sapiens (Human)) | BDBM50175284 (CHEMBL3808554) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation... | ACS Med Chem Lett 7: 487-92 (2016) BindingDB Entry DOI: 10.7270/Q2CV4KP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase types 2 (SphK2) (Homo sapiens (Human)) | BDBM50175284 (CHEMBL3808554) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of human SphK2 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation... | ACS Med Chem Lett 7: 487-92 (2016) BindingDB Entry DOI: 10.7270/Q2CV4KP5 | |||||||||||
More data for this Ligand-Target Pair |