BDBM50175352 2-chloro-6-(3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile::CHEMBL199785

SMILES: CC(C)(Cc1ccc2ccccc2c1)NCCCOc1cccc(Cl)c1C#N

InChI Key: InChIKey=XJFHSDFNPRKVBK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50175352 (2-chloro-6-(3-(2-methyl-1-(naphthalen-2-yl)propan-...) Show SMILES CC(C)(Cc1ccc2ccccc2c1)NCCCOc1cccc(Cl)c1C#N Show InChI InChI=1S/C24H25ClN2O/c1-24(2,16-18-11-12-19-7-3-4-8-20(19)15-18)27-13-6-14-28-23-10-5-9-22(25)21(23)17-26/h3-5,7-12,15,27H,6,13-14,16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR				Bioorg Med Chem Lett 15: 5478-82 (2005) Article DOI: 10.1016/j.bmcl.2005.08.095 BindingDB Entry DOI: 10.7270/Q2WS8STX
					More data for this Ligand-Target Pair