BDBM50175388 (S)-1-(3-methoxyphenoxy)-3-(1-(4-methoxyphenyl)-2-methylpropan-2-ylamino)propan-2-ol::CHEMBL201381

SMILES: COc1ccc(CC(C)(C)NC[C@H](O)COc2cccc(OC)c2)cc1

InChI Key: InChIKey=OXVYMZAJPRGSLF-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50175388 ((S)-1-(3-methoxyphenoxy)-3-(1-(4-methoxyphenyl)-2-...) Show SMILES COc1ccc(CC(C)(C)NC[C@H](O)COc2cccc(OC)c2)cc1 Show InChI InChI=1S/C21H29NO4/c1-21(2,13-16-8-10-18(24-3)11-9-16)22-14-17(23)15-26-20-7-5-6-19(12-20)25-4/h5-12,17,22-23H,13-15H2,1-4H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR				Bioorg Med Chem Lett 15: 5478-82 (2005) Article DOI: 10.1016/j.bmcl.2005.08.095 BindingDB Entry DOI: 10.7270/Q2WS8STX
					More data for this Ligand-Target Pair