BDBM50175542 7-Oxo-7,8-dihydro-6H-quinolizine-4-carboxylic acid hydroxycarbamoylmethyl-amide::CHEMBL414852

SMILES: ONC(=O)CNC(=O)C1=CC=CC2=CCC(=O)CN12

InChI Key: InChIKey=UUBHICMMWXWXCP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175542   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50175542 (7-Oxo-7,8-dihydro-6H-quinolizine-4-carboxylic acid...) Show SMILES ONC(=O)CNC(=O)C1=CC=CC2=CCC(=O)CN12 |c:10,t:8,12| Show InChI InChI=1S/C12H13N3O4/c16-9-5-4-8-2-1-3-10(15(8)7-9)12(18)13-6-11(17)14-19/h1-4,19H,5-7H2,(H,13,18)(H,14,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
De Novo Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory concentration against (MMP-1) matrix metalloproteinase-1				J Med Chem 48: 6585-96 (2005) Article DOI: 10.1021/jm050196j BindingDB Entry DOI: 10.7270/Q20K284B
					More data for this Ligand-Target Pair