BDBM50175550 CHEMBL198377::N-Hydroxy-4-oxo-4-[4-(pyridin-4-yloxy)-phenyl]-butyramide

SMILES: ONC(=O)CCC(=O)c1ccc(Oc2ccncc2)cc1

InChI Key: InChIKey=MOJJTIYQNPKLMH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50175550 (CHEMBL198377 | N-Hydroxy-4-oxo-4-[4-(pyridin-4-ylo...) Show SMILES ONC(=O)CCC(=O)c1ccc(Oc2ccncc2)cc1 Show InChI InChI=1S/C15H14N2O4/c18-14(5-6-15(19)17-20)11-1-3-12(4-2-11)21-13-7-9-16-10-8-13/h1-4,7-10,20H,5-6H2,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
De Novo Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards (MMP-1) matrix metalloproteinase-1				J Med Chem 48: 6585-96 (2005) Article DOI: 10.1021/jm050196j BindingDB Entry DOI: 10.7270/Q20K284B
					More data for this Ligand-Target Pair