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SMILES: CCc1cc(Nc2cc(=O)n(CCCCCN3CCc4c(C3)[nH]c3ccc(OC)cc43)c(=O)[nH]2)ccc1C

InChI Key: InChIKey=GCDXLKPFAHFJDE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176081   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA polymerase III PolC-type


(Bacillus subtilis)		BDBM50176081
PNG
(6-(3-Ethyl-4-methyl-phenylamino)-3-[5-(6-methoxy-1...)
Show SMILES CCc1cc(Nc2cc(=O)n(CCCCCN3CCc4c(C3)[nH]c3ccc(OC)cc43)c(=O)[nH]2)ccc1C
Show InChI InChI=1S/C30H37N5O3/c1-4-21-16-22(9-8-20(21)2)31-28-18-29(36)35(30(37)33-28)14-7-5-6-13-34-15-12-24-25-17-23(38-3)10-11-26(25)32-27(24)19-34/h8-11,16-18,31-32H,4-7,12-15,19H2,1-3H3,(H,33,37)
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents
Article
PubMed
 110n/an/an/an/an/an/an/an/a



GLSynthesis Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against Bacillus subtilis DNA polymerase IIIC using [3H]dTMP 250 pM (30 degree C for 10 min)

J Med Chem 48: 7063-74 (2005)


Article DOI: 10.1021/jm050517r
BindingDB Entry DOI: 10.7270/Q2W66MJN
More data for this
Ligand-Target Pair