BDBM50176255 2-((5,7-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-1H-benzo[d]imidazole-5-carboxamidine::CHEMBL202394

SMILES: NC(=N)c1ccc2nc(Cc3nc4c(F)cc(F)cc4[nH]3)[nH]c2c1

InChI Key: InChIKey=XPYXMPGQSDUBFA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50176255 (2-((5,7-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-...) Show SMILES NC(=N)c1ccc2nc(Cc3nc4c(F)cc(F)cc4[nH]3)[nH]c2c1 Show InChI InChI=1S/C16H12F2N6/c17-8-4-9(18)15-12(5-8)23-14(24-15)6-13-21-10-2-1-7(16(19)20)3-11(10)22-13/h1-5H,6H2,(H3,19,20)(H,21,22)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Binding affinity to FXa in presence of Zn2+				Bioorg Med Chem Lett 16: 710-3 (2005) Article DOI: 10.1016/j.bmcl.2005.10.023 BindingDB Entry DOI: 10.7270/Q2VM4BSJ
					More data for this Ligand-Target Pair