BDBM50176292 CHEMBL373278::ethyl 2-(3-(4-fluorophenylsulfonyl)ureido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate

SMILES: CCOC(=O)c1c(NC(=O)NS(=O)(=O)c2ccc(F)cc2)sc2CCCCc12

InChI Key: InChIKey=WMSLBPHYISUUHI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50176292 (CHEMBL373278 | ethyl 2-(3-(4-fluorophenylsulfonyl)...) Show SMILES CCOC(=O)c1c(NC(=O)NS(=O)(=O)c2ccc(F)cc2)sc2CCCCc12 Show InChI InChI=1S/C18H19FN2O5S2/c1-2-26-17(22)15-13-5-3-4-6-14(13)27-16(15)20-18(23)21-28(24,25)12-9-7-11(19)8-10-12/h7-10H,2-6H2,1H3,(H2,20,21,23)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
ViroPharma Inc Curated by ChEMBL					Assay Description Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymerase				Bioorg Med Chem Lett 16: 100-3 (2005) Article DOI: 10.1016/j.bmcl.2005.09.047 BindingDB Entry DOI: 10.7270/Q2M32VBT
					More data for this Ligand-Target Pair