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BDBM50176486 (5-cyano-6-fluoro-8-methyl-1-propyl-3,4-dihydro-1H-benzo[4,5]thieno[2,3-c]pyran-1-yl)-acetic acid::CHEMBL200405

SMILES: CCCC1(CC(O)=O)OCCc2c1sc1c(C)cc(F)c(C#N)c21

InChI Key: InChIKey=XEPYXSNMTYAXLO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176486   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50176486
PNG
((5-cyano-6-fluoro-8-methyl-1-propyl-3,4-dihydro-1H...)
Show SMILES CCCC1(CC(O)=O)OCCc2c1sc1c(C)cc(F)c(C#N)c21
Show InChI InChI=1S/C18H18FNO3S/c1-3-5-18(8-14(21)22)17-11(4-6-23-18)15-12(9-20)13(19)7-10(2)16(15)24-17/h7H,3-6,8H2,1-2H3,(H,21,22)
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Displacement of [alpha-32P]GTP from recombinant HCV NS5B RNA dependent RNA polymerase


Bioorg Med Chem Lett 16: 457-60 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.114
BindingDB Entry DOI: 10.7270/Q25X28H8
More data for this
Ligand-Target Pair