BDBM50176486 (5-cyano-6-fluoro-8-methyl-1-propyl-3,4-dihydro-1H-benzo[4,5]thieno[2,3-c]pyran-1-yl)-acetic acid::CHEMBL200405
SMILES: CCCC1(CC(O)=O)OCCc2c1sc1c(C)cc(F)c(C#N)c21
InChI Key: InChIKey=XEPYXSNMTYAXLO-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus) | BDBM50176486 ((5-cyano-6-fluoro-8-methyl-1-propyl-3,4-dihydro-1H...) | UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [alpha-32P]GTP from recombinant HCV NS5B RNA dependent RNA polymerase | Bioorg Med Chem Lett 16: 457-60 (2005) Article DOI: 10.1016/j.bmcl.2005.08.114 BindingDB Entry DOI: 10.7270/Q25X28H8 | |||||||||||
More data for this Ligand-Target Pair |